Publikationen

2024

Antipova V, Heimes D, Seidel K, Schulz J, Schmitt O, Holzmann C, Rolfs A, Bidmon H.-J, González de San Román Martín E, Huesgen P F, Amunts K, Keiler J, Hammer N, Witt M and Wree A (2024) Differently increased Volumes of Multiple Brain Areas in Npc1 Mutant Mice Following Various Drug Treatments. Frontiers in Neuroanatomy 18:1430790
Küpker W, Bullerdiek J and Felberbaum R (2024) Infertilität bei Endometriose und Adenomyose – welche Bedeutung hat die Implantation? Gynäkologische Endokrinologie

2023

Küpker W, Felberbaum R and Bullerdiek J (2023) Endometriose und Adenomyose. Gynäkologische Endokrinologie
Hühns M, Ameziane N, Holzmann C, Al-Ali R and Prall F (2023) Clonal and “Intrinsic” Heterogeneity of Somatic Variants in Microsatellite-Stable Colorectal Carcinomas and Their Metastases. Laboratory Investigation 103(7): 100132
Antipova V, Steinhoff L-M, Holzmann C, Rolfs A, Hempel CJ, Witt M and Wree A (2023) Organ Weights in NPC1 Mutant Mice Partly Normalized by Miglustat, Cyclodextrin, and Combination Treatment. International Journal of Molecular Sciences 24(1): 573

Buchbeiträge

Jörn Bullerdiek , Christine Süßmuth (2023) Warum Musik in unseren Genen liegt.Springer Berlin, Heidelberg, ISBN 978-3-662-67374-4
Podcast: „Warum Musik in unseren Genen liegt“ – Prof. Dr. Jörn Bullerdiek und Christine Süßmuth (#10)

2022

Bullerdiek J, Helmke BM, Laban M (2022) Endometrial polyps-neoplastic lesions or not? Is it time to close the files? Mod Pathol https://doi.org/10.1038/s41379-022-01162-z
Krysewski L-M, Power Guerra N, Glatzel A, Holzmann C, Antipova V, Schmitt O, Yu-Taeger L, Nguyen HP, Wree A, Witt M. Differential Cellular Balance of Olfactory and Vomeronasal Epithelia in a Transgenic BACHD Rat Model of Huntington’s Disease. International Journal of Molecular Sciences. 2022; 23(14):7625
Bullerdiek J, Reisinger E, Rommel B, Dotzauer A. (2022) ABO blood groups and the risk of SARS-CoV-2 infection. Protoplasma https://doi.org/10.1007/s00709-022-01754-1
Alberts T, Antipova V, Holzmann C, Hawlitschka A, Schmitt O, Kurth J, Stenzel J, Lindner T, Krause B, Wree A, Witt M. (2022) Olfactory bulb D2/D3 receptor availability after intrastriatal botulinum neurotoxin–A injection in a unilateral 6-OHDA rat model of Parkinson’s disease. Toxins14: 94

2021

Bullerdiek J. (2021) Preprint publications in a time of COVID-19. F1000 Blogs
Bullerdiek J, Bock-Steinweg U. (2021) COVID-19: women with PCO syndrome at higher risk. Gynäkologische Endokrinologie 19: 319–320
Antipova V, Holzmann, C, Hawlitschka A, Witt M, Wree A. (2021) Antidepressant-Like Properties of Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson’s Disease. Toxins 13: 505
Holzmann C, Witt M, Rolfs A, Antipova V, Wree A. (2021) Gender-Specific Effects of Two Treatment Strategies in a Mouse Model of Niemann-Pick Disease Type C1. International Journal of Molecular Sciences 22: 2539
Gottlieb A, Flor I, Nimzyk R, Burchardt L, Helmke B, Langenbuch M, Spiekermann M, Feidicke, S, Bullerdiek J. (2021) The expression of miRNA encoded by C19MC and miR-371-3 strongly varies among individual placentas but does not differ between spontaneous and induced abortions. Protoplasma 258: 209–218
Völkner C, Liedtke M, Petters J, Lukas J, Murua Escobar H, Knuebel G, Bullerdiek J, Holzmann C, Hermann A, Frech M J. (2021) Generation of an iPSC line (AKOSi004-A) from fibroblasts of a female adult NPC1 patient, carrying the compound heterozygous mutation p.Val1023Serfs*15/p.Gly992Arg and of an iPSC line (AKOSi005-A) from a female adult control individual. Stem Cell Research 50:102127

2020

Burchardt L, Gottlieb A, BHelmke BM, Wosniok W, Kuepker W, Bullerdiek J. (2020) Expression patterns of HMGA2 in the placenta during pregnancy. medRxiv 20245092
Petters J, Völkner C, Krohn S, Murua Escobar H, Bullerdiek J, Reuner U, MJ, Hermann A, Lukas J. (2020) Generation of two induced pluripotent stem cell lines from a female adult homozygous for the Wilson disease associated ATP7B variant p.H1069Q (AKOSi008-A) and a healthy control (AKOSi009-A). Stem Cell Research 49:102079
Völkner C, Liedtke M, Petters J, Huth K, Knuebel G, Murua Escobar H, Bullerdiek J, Lukas J, Hermann A, Frech MJ. (2020) Generation of an iPSC line (AKOSi006-A) from fibroblasts of a NPC1 patient, carrying the homozygous mutation p.I1061T (c.3182 T > C) and a control iPSC line (AKOSi007-A) using a non-integrating Sendai virus system. Stem Cell Research 49:102056
Bullerdiek J. (2020) COVID-19 and blood groups – there is an elephant in the room, but who cares? Do we need additional rules for preprints? F1000Research 2020, 9:1139
Bullerdiek J. (2020) Blood type A associated with critical COVID-19 and death in a Swedish cohort - a critical comment. Critical Care 24:547
Gottlieb A, Flor I, Nimzyk R, Burchardt, L, Helmke B , Langenbuch M, Spiekermann M, Feidicker S, and Bullerdiek J. (2020) The expression of miRNA encoded by C19MC and miR 371-3 strongly varies among individual placentas but does not differ between spontaneous and induced abortions. Protoplasma
Holzmann C, Helmke B and Bullerdiek J. Gross genetic alterations and genetic heterogeneity in a periductal stromal tumor of the breast. Mol Cytogenet 13:49
Küpker W, Plathow D, Bullerdiek J and Felberbaum R. (2020) Neue Behandlungsoptionen mit GnRH-Antagonisten bei Endometriose und Uterus myomatosus. Gynäkologische Endokrinologie
Bullerdiek J and Bock-Steinweg U. Das GnRHR-Gen, seine Mutationen und deren Manifestation. Gynäkologe 53: 502–509
Bullerdiek J, Holzmann C and Rommel B. (2020) Die Rolle der HMGA-Proteine („high mobility group AT-hook“) bei Proliferation und Differenzierung mesenchymaler Zellen und Gewebe. Gefäßchirurgie 25: 332–338
Foriata R, Friemel J, Günther K, Behrens T, Bullerdiek J and Nimzyk R. (2020) Causal discovery of gene regulation with incomplete data. J. R. Statist. Soc. A:12565
Hawlitschka A, Berg C, Schmitt O, Holzmann C, Wree A and Antipova V. (2020) Repeated intrastriatal application of Botulinum neurotoxin-A did not influence choline acetyltransferase-immunoreactive interneurons in hemiparkinsonian rat brain - A histological, stereological and correlational analysis. Brain Res 146877
Bullerdiek J. (2020) COVID-19 challenging cell biology. Protoplasma 257:1-2
Holzmann C, Kuepker W, Rommel B, Helmke B and Bullerdiek J. (2020) Reasons to reconsider risk figures associated with power morcellation of uterine fibroids. In vivo 34:1-9

Buchbeiträge

Wree A, Hawlitschka A, Holzmann C, Witt M, Kurth J, Lindner T, Mann T, Antipova V. Interlinking potential therapy with botulinum neurotoxin-A and Parkinson´s disease. Chapter 38 in: The Neuroscience of Parkinson´s Disease. Edited by Victor R. Preedy, Elsevier, ISBN 9780128159583

2019

Zhan J, Yakimov V, Rühling S, Fischbach F, Nikolova E, Joost S, Kaddatz H, Greiner T, Frenz J, Holzmann C and Kipp M. (2019) High Speed Ventral Plane Videography as a Convenient Tool to Quantify Motor Deficits during Pre-Clinical Experimental Autoimmune Encephalomyelitis.
Cells 8:1439
Bräuer A U, Kuhla A, Holzmann C, Wree A and Witt M. (2019) Current Challenges in understanding the cellular and molecular mechanisms in Niemann-Pick Disease Type C1. Int J Mol Sci 20:4392
Hühns M, Holzmann C and Prall F. (2019) Cancer in a bang: panel next-generation gene sequencing and OncoScan array analysis of a minute colorectal adenocarcinoma and its precursor adenoma. Histopathology 75:605-608
Bullerdiek J and Küpker W. (2019) Myome - Was liegt da in der DNA? Der Gynäkologe 2019
Antipova A, Holzmann C, Hawlitschka A and Wree A. (2019) Botulinum neurotoxin-A injected intrastriatally into hemiparkinsonian rats improves the initiation time for left and right forelimbs in both forehand and backhand directions. Int J Mol Sci 20:992
Maletzki C, Hühns M, Bauer I, Prall F, Junghanss C, Henze L. (2019) Suspected Hereditary Cancer Syndromes in Young Patients: Heterogeneous Clinical and Genetic Presentation of Colorectal Cancers. The Oncologist 24:877-882
Bullerdiek J. (2019) Bacteria acting with tumorigenic chaperones.
Protoplasma 256:291–292

Buchbeiträge

Fehr A, Bullerdiek J, Jaekel T and Löning T. (2019) Molecular Characterization of Salivary Gland Carcinomas. Chapter in: Salivary Gland Cancer. Edited by Licitra L, Locati L. Springer, Cham

2018

Hawlitschka A, Holzmann C, Wree A, Antipova V. (2018) Repeated intrastriatal botulinum neurotoxin-A injection in hemiparkinsonian rats increased the beneficial effect on rotational behavior. Toxins 10:368-389
Antipova A, Wree A, Holzmann C, Mann T, Palomero-Gallagher N, Zilles K, Schmitt O and Hawlitschka A. (2018) Unilateral Botulinum neurotoxin-A injection into the striatum of C57BL/6 mice leads to a different motor behavior compared to rats. Toxins 10:295
Bullerdiek J and Rommel B. (2018) Factors targeting MED12 to drive tumorigenesis? [version 1; referees: 2 approved with reservations] F1000Research 7:359
Holzmann C, Saager C, Mechtersheimer G, Koczan D, Helmke BM and Bullerdiek J. (2018) Malignant transformation of uterine leiomyoma to myxoid leiomyosarcoma after morcellation associated with ALK rearrangement and loss of 14q. Oncotarget 9:27595-27604

2017

Hawlitschka A, Holzmann C, Witt S, Spiewok J, Neumann A-M, Schmitt O, Wree A and Antipova V. (2017) Intrastriatally injected botulinum neurotoxin-A differently effects cholinergic and dopaminergic fibers in C57BL/6 mice. Brain Research, 1676:46-56
Kloth L, Gottlieb A, Helmke BM, Wosniok W and Bullerdiek J. (2017) Expression of HMGA2 in fetal placenta correlates with gestational age. submitted to BMC Women´s Health
Holzmann C, Koczan D, Loening T, Rommel B, Bullerdiek J. (2017) Case Report: A low-grade uterine leiomyosarcoma showing multiple genetic aberrations including a bi-allelic loss of the retinoblastoma gene locus as well as germ-line uniparental disomy for part of the long arm of chromosome 22. Anticancer Research 37:2233
Antipova V, Holzmann C, Schmitt O, Wree A and Hawlitschka A. (2017) Behavioral effects of Botulinum neurotoxin A injected ipsilaterally and contralaterally into the striatum in the rat 6-OHDA model of unilateral Parkinson’s disease. Frontiers in Behavioral Neuroscience 11:119
Meyer A, Wree A, Holzmann C, Schmitt O, Rolfs A and Witt M. (2017) Increased regenerative capacity of the olfactory epithelium in Niemann-Pick disease type C1. Int J Med Sci 18:777
Bloch J, Holzmann C, Koczan D, Helmke BM, Bullerdiek J. (2017) Loss of MED12-mutated leiomyoma cells occurs independent of passaging during in vitro growth. Oncotarget 137(2):123-128
Günther K, Foraita R, Friemel J, Günther F, Bullerdiek J, Nimzyk R, Markowski DN, Behrens T, Ahrens W. (2017) The Stem Cell Factor HMGA2 Is Expressed in Non-HPV-Associated Head and Neck Squamous Cell Carcinoma and Predicts Patient Survival of Distinct Subsites. Cancer Epidemiol Biomarkers Prev. 26:197-205
Maletzki C, Hühns M, Bauer I, Ripperger,T, Mork MM, Vilar, E, Klöcking S, Zettl, H, Prall, F, Linnebacher (2017) Frameshift mutational target gene analysis identifies similarities and differences in constitutional mismatch repair-deficiency and Lynch syndrome. Mol Carcinog 56:1753-1764

Buchbeiträge

Bullerdiek J (2017) Lipomas and Uterine Leiomyomas. Chapter in: Reference Module in Life Sciences, Elsevier, ISBN 9780128096338
Bell D, Bullerdiek J et al. (2017) Pleomorphic adenoma. Chapter 1-7A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 33, ISBN 978-92-832-2438-9
Thompson, LDR, Bullerdiek J et al. (2017) Leiomyoma. Chapter 1-10A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 47, ISBN 978-92-832-2438-9
Thompson, LDR, Bullerdiek J et al. (2017) Haemangioma .Chapter 1-10B in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 47, ISBN 978-92-832-2438-9
Thompson, LDR, Bullerdiek J et al. (2017) Schwannoma. Chapter 1-10C in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 48, ISBN 978-92-832-2438-9
Thompson, LDR, Bullerdiek J et al. (2017) Neurofibroma. Chapter 1-10D in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 49, ISBN 978-92-832-2438-9
Bullerdiek J et al. (2017) Angiosarcoma. Chapter 1-8E in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 38, ISBN 978-92-832-2438-9
Bullerdiek J et al. (2017) Synovial Sarcoma. Chapter 1-8H in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 41, ISBN 978-92-832-2438-9
Baumhoer D, Bullerdiek J, Nicolai P. (2017) Chordoma. Chapter 2-8A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 76, ISBN 978-92-832-2438-9
Bell D, Bullerdiek J, Hunt JL. (2017) Pleomorphic adenoma. Chapter 3-6B in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 99, ISBN 978-92-832-2438-9
Allen CM, Bullerdiek J (2017) Congenital granular cell epulis. Chapter 4-5A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 119, ISBN 978-92-832-2438-9
Bullerdiek J et al. (2017)Rhabdomyoma. Chapter 4-6B in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 122, ISBN 978-92-832-2438-9
Bullerdiek Jet al.(2017) Lymphangioma. Chapter 4-6C in:El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ(Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 122, ISBN 978-92-832-2438-9
Bullerdiek Jet al.(2017) Haemangioma (suptypes). Chapter 4-6D in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 123, ISBN 978-92-832-2438-9
Bell D, Bullerdiek J et al. (2017) Pleomorphic adenoma. Chapter 5-3A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 139, ISBN 978-92-832-2438-9
Bell D, Bullerdiek J et al. (2017) Pleomorphic adenoma. Chapter 7-4A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 185, ISBN 978-92-832-2438-9
Flucke U, Bullerdiek J et al. (2017) Haemangioma. Chapter 7-6A in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 198, ISBN 978-92-832-2438-9
Ihrler S, Bullerdiek J et al. (2017) Lipoma/Sialolipoma. Chapter 7-6B in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 198, ISBN 978-92-832-2438-9
Ihrler S, Bullerdiek J et al. (2017) Nodular fasciitis. Chapter 7-6C in: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (Editors). Pathology and Genetics of Head and Neck Tumours. Fourth edition, Volume 9, 199, ISBN 978-92-832-2438-9

2016

Schlegel V, Thieme M, Holzmann C, Witt M, Grittner U, Rolfs A, Wree A. (2016) Pharmacologic treatment assigned for Niemann Pick type C1 disease partly changes behavioral traits in wild type mice. Int J Mol Sci 17:1866
Bullerdiek J. (2016) Somatische Mutationen bei Uterus-Myomen: Bedeutung für Pathogenese und klinische Relevanz. DKFZ Zeitschrift Einblick 1/2016:14
Günther K, Foraita R, Friemel J, Günther F, Bullerdiek J, Nimzyk R, Markowski DN, Behrens T, Ahrens W. (2016) The stem cell factor HMGA2 is expressed in non-HPV associated head and neck squamous cell carcinoma and predicts patient survival of distinct subsites. Cancer Epidemiol Biomarkers Prev. [Epub ahead of print]
Flor, I., Spiekermann, M., Löning, T., Dieckmann, K.-P., Belge, G., Bullerdiek, J. (2016) Expression of microRNAs of C19MC in different histologic types of testicular germ cell tumours. Cancer Genomics and Proteomics 13:281-289
Friemel J, Foraita R, Günther K, Heibeck M, Günther F, Pflueger M, Pohlabeln H, Behrens T, Bullerdiek J, Nimzyk R, Ahrens W. (2016) Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients. BMC Oral Health. 16:33
Bullerdiek J, Dotzauer, A and Bauer, I. (2016) The mitotic spindle: Linking teratogenic effects of Zika virus with human genetics? Molecular Cytogenetics 9:32
Rommel B, Holzmann C and Bullerdiek J. (2016) Malignant mesenchymal tumors of the uterus – time to advocate a genetic classification.
Expert Review of Anticancer Therapy 16:1155
Dieckmann KP, Spiekermann M, Balks T, Ikogho R, Anheuser P, Wosniok W, Loening T, Bullerdiek J, Belge G. (2016) MicroRNA miR-371a-3p - A Novel Serum Biomarker of Testicular Germ Cell Tumors: Evidence for Specificity from Measurements in Testicular Vein Blood and in Neoplastic Hydrocele Fluid. Urol Int. 97:76-83
Holzmann C, Löning T, and Bullerdiek J. Hyperhaploid uterine mesenchymal tumors - a novel genetic subgroup? Cancer Genetics 209: 278-281

2015

Holzmann C, Markowski DN, von Leffern, Löning C and Bullerdiek J. (2015) Patterns of chromosomal abnormalities that can improve diagnosis of uterine smooth muscle tumors. Anticancer Research 35:6445
Markowski DN, Holzmann C and Bullerdiek J. (2015) Genetic alterations in uterine fibroids – A new direction for pharmacological intervention? Expert Opinion On Therapeutic Targets 19:1485-94
Holzmann C, Markowski DN, Bartnitzke S, Koczan D, Helmke BM and Bullerdiek J. (2015) A rare coincidence of different types of driver mutations among uterine leiomyomas of one patient. Molecular Cytogenetics8:76
Kloth L, Gottlieb A, Helmke BM, Wosniok W, Löning T, Burchardt K, Belge G, Günther K, and Bullerdiek J. (2015): HMGA2 expression distinguishes between different types of post-pubertal testicular germ cell tumours. The Journal of Pathology: Clinical Research 1:239-251
Bullerdiek J (2015) Somatische Mutationen bei Uterus-Myomen: Bedeutung für
Pathogenese und klinische Relevanz. GYNE 4: 22-24
Flor I and Bullerdiek J. (2015) MicroRNAs als Mediatoren des embryomaternalen Dialogs. Gynäkologische Endokrinologie 13:110–114
Spiekermann M, Dieckmann KP, Balks, J, Bullerdiek J, Belge G. (2015) Is relative quantification dispensable for measurement of microRNAs as serum biomarkers in germ cell tumors? Anticancer Research 35:117-21
Spiekermann M, Belge G, Winter N, Ikogho R, Balks T, Bullerdiek J, Dieckmann KP. (2015). MicroRNA miR-371a-3p in serum of patients with germ cell tumours: evaluations for establishing a serum biomarker. Andrology 3:78-84
Teipel S, Ehlers I, Erbe A, Holzmann C, Lau E, Hauenstein K, Berger C. (2015) Structural Connectivity Changes Underlying Altered Working Memory Networks in Mild Cognitive Impairment: A Three-Way Image Fusion Analysis. J Neuroimaging 25:634-42

Buchbeiträge

Jörn Bullerdiek and David Gisselsson (2015) Tumors of endocrine glands. In: Cancer Cytogenetics: Chromosomal and Molecular Genetic Aberrations of Tumor Cells, 4th Edition Editors-in-Chief: Sverre Heim and Felix Mitelman, Wiley-Blackwell, ISBN: 978-1-118-79553-8
Ingrid Bauer: Fragiles X-Syndrom und FMR1-assoziierte Erkrankungen - klinische und genetische Aspekte.
In: Frank Häßler, David Pittrow, Michael Seidel (Hrsg.) Das Fragile X-Syndrom, UNI-MED Verlag AG Bremen, 1. Auflage 2015, ISBN 978-3-8374-2300-6
S. Weirich, Ingrid Bauer: Eine vom Fragilen X-Syndrom (FRX) betroffene Familie - ein Fallbericht.
In: Frank Häßler, David Pittrow, Michael Seidel (Hrsg.) Das Fragile X-Syndrom, UNI-MED Verlag AG Bremen, 1. Auflage 2015, ISBN 978-3-8374-2300-6

2014

Holzmann C, Markowski DN, Koczan D, Küpker W, Helmke B and Bullerdiek J. (2014) Cytogenetically normal uterine leiomyomas without MED12-mutations - a source to identify unknown mechanisms of the development of uterine smooth muscle tumors. Molecular Cytogenetics 7:88.
Seifert W, Meinecke P, Krüger G, Rossier E, Heinritz W, Wüsthof A, Horn D. (2014) Expanded spectrum of exon 33 and 34 mutations in SRCAP and follow-up in patients with Floating-Harbor syndrome. BMC Med Genet. 15:127
Schanze D, Neubauer D, Cormier-Daire V, Delrue MA, Dieux-Coeslier A, Hasegawa T, Holmberg EE, Koenig R, Krueger G, Schanze I, Seemanova E, Shaw AC, Vogt J, Volleth M, Reis A, Meinecke P, Hennekam RC, Zenker M. (2014) Deletions in the 3' part of the NFIX gene including a recurrent Alu-mediated deletion of exon 6 and 7 account for previously unexplained cases of Marshall-Smith syndrome. Human Mutation 35:1092–1100
Thiele K, Holzmann C, Solano E, Zahner G, and Arck PC (2014) Comparative sensitivity analyses of quantitative polymerase chain reaction and flow cytometry in detecting cellular microchimerism in murine tissues. Journal of Immunological Methods 406:74
Drosch M, Schmidt N, Markowski DN, Zollner TM, Koch M, Bullerdiek J. (2014) The CD24 hi smooth muscle subpopulation is the predominant fraction in uterine fibroids. Mol Hum Reprod 20:664
Holzmann C, Markowski DN, Koczan D, Helmke BM and Bullerdiek J (2014) Genome-wide acquired uniparental disomy as well as chromosomal gains and losses in an uterine epithelioid leiomyoma. Mol Cytogenet 7: 19
Thies HW, Nolte I, Wenk H, Mertens F, Bullerdiek J, Markowski DN. (2014) Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue. Obesity 22:141-50
Markowski DN, Tadayyon M, Bartnitzke S, Belge G, Maria Helmke B, Bullerdiek J.(2014) Cell cultures in uterine leiomyomas: Rapid disappearance of cells carrying MED12 mutations. Genes Chromosomes Cancer 53:317
Klemke M, Müller MH, Wosniok W, Markowski DN, Nimzyk R, Helmke BM, Bullerdiek J. (2014) Correlated Expression of HMGA2 and PLAG1 in Thyroid Tumors, Uterine Leiomyomas and Experimental Models. PLoS One 9:e88126
Markowski DN, Helmke BM, Bartnitzke S, Löning T, and Bullerdiek J (2013) Uterine fibroids - do we deal with more than one disease? International Journal of Gynecological Pathology 6:568

2013

Bullerdiek J, Junghanss C, Dotzauer A (2013) Small but effective – trophoblast-derived mRNAs transported via exosomes as guardians against viral infections. Future Virology 8:1049-1052.
Markowski DN, Bullerdiek J. (2013) Chromothripsis in uterine leiomyomas. Comment on Characterization of uterine leiomyomas by whole-genome sequencing. N Engl J Med 369(22):2160
Gillis AJ, Rijlaarsdam MA, Eini R, Dorssers LC, Biermann K, Murray MJ, Nicholson JC, Coleman N, Dieckmann K, Belge G, Bullerdiek J, Xu T, Bernard N, Looijenga LH (2013) Targeted serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: A proof of principle. Molecular Oncology 7:1083
Markowski DN, Thies HW, Gottlieb A, Wenk H, Wischnewsky M, Bullerdiek J (2013) HMGA2 expression in white adipose tissue linking cellular senescence with diabetes. Genes Nutr 8:449
Müller MH, Drieschner N, Focken T, Bartnitzke S, Winter N, Klemke M, Bullerdiek J (2013) HMGA2 Expression in the PC-3 Prostate Cancer Cell Line Is Autonomous of Growth Factor Stimulation. Anticancer Res. 33:3069–3078.
Holzmann C, Bauer I, Meyer P (2013) Co-occurrence of multiple sclerosis and cancer in a BRCA1 positive family. Eur J Med Genet 56:577
Markowski DN, Nimzyk R, Belge G, Löning T, Helmke BM, Bullerdiek J (2013) Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability. Mol Cytogenet 6:23.
Markowski DN, Huhle S, Nimzyk R, Stenman G, Löning T, Bullerdiek J (2013) MED12 mutations occurring in benign and malignant mammalian smooth muscle tumors. Genes Chromosomes Cancer 52:297–304.
Kuhla A, Lange S, Holzmann C, Maass F, Petersen J, Vollmar B, et al. (2013) Lifelong caloric restriction increases working memory in mice. PloS one 8(7): e68778.
Hovakimyan M, Maass F, Petersen J, Holzmann C, Witt M, Lukas J, et al. (2013) Combined therapy with cyclodextrin/allopregnanolone and miglustat improves motor but not cognitive functions in Niemann-Pick Type C1 mice. Neuroscience 252:201
Kljajevic V, Meyer P, Holzmann C, Dyrba M, Kasper E, Bokde AL, Fellgiebel A, Meindl T, Hampel H, Teipel S, EDSD study group (2013) The ε4 genotype of apolipoprotein E and white matter integrity in Alzheimer's disease. Alzheimer's and dementia 10:401
Drosch M, Bullerdiek J, Zollner TM, Prinz F, Koch M, Schmidt N (2013) A novel mouse model that closely mimics human uterine leiomyomas. Fertil. Steril. 99:927-935.e6.

Buchbeiträge

Markowski DN and Bullerdiek J (2013) Lipomas and Leiomyomas. In: Brenner's Encyclopedia of Genetics (Second Edition) Editors-in-Chief: Stanley Maloy and Kelly Hughes, Elsevier Inc.

2012

Holzmann C, Dräger D, Mix E, Hawlitschka A, Antipova V, Benecke R, Wree A (2012) Effects of intrastriatal botulinum neurotoxin A on the behavior of Wistar rats. Behav Brain Res. 234:107-16.

2010

Boy J, Schmidt T, Schumann U, Grasshoff U, Unser S, Holzmann C, Schmitt I, Karl T, Laccone F, Wolburg H, Ibrahim S, Riess O (2010) A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats. Neurobiol Dis 37:284-293.
Klopocki E, Hennig BP, Dathe K, Koll R, de RT, Baten E, Blom E, Gillerot Y, Weigel JF, Kruger G, Hiort O, Seemann P, Mundlos S (2010) Deletion and point mutations of PTHLH cause brachydactyly type E. Am J Hum Genet 86:434-439.

2009

Boy J, Schmidt T, Wolburg H, Mack A, Nuber S, Bottcher M, Schmitt I, Holzmann C, Zimmermann F, Servadio A, Riess O (2009) Reversibility of symptoms in a conditional mouse model of spinocerebellar ataxia type 3. Hum Mol Genet 18:4282-4295.
Neumann TE, Allanson J, Kavamura I, Kerr B, Neri G, Noonan J, Cordeddu V, Gibson K, Tzschach A, Kruger G, Hoeltzenbein M, Goecke TO, Kehl HG, Albrecht B, Luczak K, Sasiadek MM, Musante L, Laurie R, Peters H, Tartaglia M, Zenker M, Kalscheuer V (2009) Multiple giant cell lesions in patients with Noonan syndrome and cardio-facio-cutaneous syndrome. Eur J Hum Genet 17:420-425.
Stuhrmann M, Brakensiek K, Argyriou L, Boehm I, Hinderhofer K, Bauer I, Rhode BM, Maelzer M, Zuehlke C, Krueger G, Schmidtke J (2009) Testing the parents to confirm genotypes of CF patients is highly recommended: report of two cases. Eur J Hum Genet 17:417-419.

2008

Mrasek K, Kruger G, Bauer I, Muller-Navia J, Liehr T, Weise A (2008) A new unbalanced chromosomal abnormality in 1q31.1 to 1q32 without phenotypic consequences. Cytogenet Genome Res 121:286-287.
Nguyen HP, Metzger S, Holzmann C, Koczan D, Thiesen H-J, von Hoersten S, Riess O, Bonin M (2008) Age-dependent gene expression profile and protein expression in a transgenic rat model of Huntington's disease. PROTEOMICS - CLINICAL APPLICATIONS 2:1638-1650.
Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von HS, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O (2008) Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci 28:2471-2484.
Schulz AL, Albrecht B, Arici C, van dB, I, Buske A, Gillessen-Kaesbach G, Heller R, Horn D, Hubner CA, Korenke GC, Konig R, Kress W, Krüger G, Meinecke P, Mucke J, Plecko B, Rossier E, Schinzel A, Schulze A, Seemanova E, Seidel H, Spranger S, Tuysuz B, Uhrig S, Wieczorek D, Kutsche K, Zenker M (2008) Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome. Clin Genet 73:62-70.

2006

Boy J, Leergaard TB, Schmidt T, Odeh F, Bichelmeier U, Nuber S, Holzmann C, Wree A, Prusiner SB, Bujard H, Riess O, Bjaalie JG (2006) Expression mapping of tetracycline-responsive prion protein promoter: Digital atlasing for generating cell-specific disease models. Neuroimage 33:449-462.
Kantor O, Temel Y, Holzmann C, Raber K, Nguyen HP, Cao C, Turkoglu HO, Rutten BP, Visser-Vandewalle V, Steinbusch HW, Blokland A, Korr H, Riess O, von HS, Schmitz C (2006) Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats. Neurobiol Dis 22:538-547.
Nguyen HP, Kobbe P, Rahne H, Worpel T, Jager B, Stephan M, Pabst R, Holzmann C, Riess O, Korr H, Kantor O, Petrasch-Parwez E, Wetzel R, Osmand A, von HS (2006) Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease. Hum Mol Genet 15:3177-3194.
J. Boy, T. Schmidt, T B. Leergaard, F Odeh, S Nuber, C Holzmann, S Ibrahim, I Schmitt, S Prusiner, J G. Bjaalie, O Rieß (2006) Inducible expression of ataxin-3 in a transgenic mouse model for Spinocerebellar Ataxia Type 3. Aktuelle Neurologie AKTUEL NEUROL 33:P284
J Boy, T. Schmidt, U Schumann, J Horst, TB Leergaard, F Odeh, S Nuber, S Beck, C Holzmann, S Ibrahim, U Grasshoff, I Schmitt (2006) Are neurodegerative processes in SCA3 reversible? A study using transgenic mouse models. Aktuelle Neurologie - AKTUEL NEUROL 34:V37

2005

Bauer A, Zilles K, Matusch A, Holzmann C, Riess O, von HS (2005) Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation. J Neurochem 94:639-650.
Steiner M, Seule M, Steiner B, Bauer I, Freund M, Kohne CH, Schuff-Werner P (2005) 5-Fluorouracil/irinotecan induced lethal toxicity as a result of a combined pharmacogenetic syndrome: report of a case. J Clin Pathol 58:553-555.

2004

Hering R, Petrovic S, Mietz EM, Holzmann C, Berg D, Bauer P, Woitalla D, Muller T, Berger K, Kruger R, Riess O (2004) Extended mutation analysis and association studies of Nurr1 (NR4A2) in Parkinson disease. Neurology 62:1231-1232.
Huebner CA, Utermann B, Tinschert S, Kruger G, Ressler B, Steglich C, Schinzel A, Gal A (2004) Intronic mutations in the L1CAM gene may cause X-linked hydrocephalus by aberrant splicing. Hum Mutat 23:526.

2003

Berg D, Holzmann C, Riess O (2003) 14-3-3 proteins in the nervous system. Nat Rev Neurosci 4:752-762.
Grundmann K, Laubis-Herrmann U, Bauer I, Dressler D, Vollmer-Haase J, Bauer P, Stuhrmann M, Schulte T, Schols L, Topka H, Riess O (2003) Frequency and phenotypic variability of the GAG deletion of the DYT1 gene in an unselected group of patients with dystonia. Arch Neurol 60:1266-1270.
Holzmann C, Kruger R, Saecker AM, Schmitt I, Schols L, Berger K, Riess O (2003) Polymorphisms of the alpha-synuclein promoter: expression analyses and association studies in Parkinson's disease. J Neural Transm 110:67-76.
Marx FP, Holzmann C, Strauss KM, Li L, Eberhardt O, Gerhardt E, Cookson MR, Hernandez D, Farrer MJ, Kachergus J, Engelender S, Ross CA, Berger K, Schols L, Schulz JB, Riess O, Kruger R (2003) Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. Hum Mol Genet 12:1223-1231.
Rolfs A, Koeppen AH, Bauer I, Bauer P, Buhlmann S, Topka H, Schols L, Riess O (2003) Clinical features and neuropathology of autosomal dominant spinocerebellar ataxia (SCA17). Ann Neurol 54:367-375.
Schoels L, Bauer I, Zuhlke C, Schulte T, Kolmel C, Burk K, Topka H, Bauer P, Przuntek H, Riess O (2003) Do CTG expansions at the SCA8 locus cause ataxia? Ann Neurol 54:110-115.
von Hoersten S, Schmitt I, Nguyen HP, Holzmann C, Schmidt T, Walther T, Bader M, Pabst R, Kobbe P, Krotova J, Stiller D, Kask A, Vaarmann A, Rathke-Hartlieb S, Schulz JB, Grasshoff U, Bauer I, Vieira-Saecker AM, Paul M, Jones L, Lindenberg KS, Landwehrmeyer B, Bauer A, Li XJ, Riess O (2003) Transgenic rat model of Huntington's disease. Hum Mol Genet 12:617-624.

2002

Bauer I, Gencik M, Laccone F, Peters H, Weber BH, Feder EH, Weirich H, Morris-Rosendahl DJ, Rolfs A, Gencikova A, Bauer P, Wenning GK, Epplen JT, Holmes SE, Margolis RL, Ross CA, Riess O (2002) Trinucleotide repeat expansions in the junctophilin-3 gene are not found in Caucasian patients with a Huntington's disease-like phenotype. Ann Neurol 51:662.
Rahner N, Holzmann C, Kruger R, Schols L, Berger K, Riess O (2002) Neurofilament L gene is not a genetic factor of sporadic and familial Parkinson's disease. Brain Res 951:82-86.
Ubl A, Berg D, Holzmann C, Kruger R, Berger K, Arzberger T, Bornemann A, Riess O (2002) 14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta. Brain Res Mol Brain Res 108:33-39.

2001

Holzmann C, Schmidt T, Thiel G, Epplen JT, Riess O (2001) Functional characterization of the human Huntington's disease gene promoter. Brain Res Mol Brain Res 92:85-97.

2000

Dörk T, Macek M Jr, Mekus F, Tümmler B, Tzountzouris J, Casals T, Krebsová A, Koudová M, Sakmaryová I, Macek M Sr, Vávrová V, Zemková D, Ginter E, Petrova NV, Ivaschenko T, Baranov V, Witt M, Pogorzelski A, Bal J, Zékanowsky C, Wagner K, Stuhrmann M, Bauer I, Seydewitz HH, Neumann T, Jakubiczka S. (2000) Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe.
Hum Genet 106(3):259-68

1998

Holzmann C, Maueler W, Petersohn D, Schmidt T, Thiel G, Epplen JT, Riess O (1998) Isolation and characterization of the rat huntingtin promoter. Biochem J 336 ( Pt 1):227-234.

1997

Holzmann C, Saecker AM, Epplen JT, Riess O (1997) Avoiding errors in the diagnosis of (CAG)n expansion in the huntingtin gene. J Med Genet 34:264.